The old-style URLs seem to work for the new images when you create them manually--the title links from the Direct Links script still work if you're on Firefox (or have GM_xmlhttpRequest available).
Old thumbnails do not match the new thumbnails.
New URLs don't indicate a revision by appending "?#########" but rather by just changing the date in the URL itself. The URL using the original upload date/time didn't work for the image I checked.
Updated