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Artist's commentary
Asagumo-nee, y'knowww, is very soooooft, whiiiich is why I liiiiike her...
Seeeee?
Asa (albeit written with a different kanji) can also mean "hemp", i.e. the plant Cannabis sativa. So, stretching a bit, Asagumo can be read as "marijuana cloud", tying in to the "Yamagumo is perpetually high on something" joke, which is also a running gag for Misumi's comics.