Popular nicovideo musician, known for bass skill, use of tissue boxes as song tally, and cosplay as Nagato Yuki. Generally accepted to be an otoko no ko.
Most artists depict Tissue Princess/Tissue-hime as Nagato Yuki herself playing the bass, so Tissue-hime tags are invoked when Yuki is sitting on a bed, playing bass, with tissues at her side, just like the real-world Tissue-hime.