Eyeshield 21 (アイシールド21, romanized as Aishīrudo Nijūichi) is a Japanese manga series written by Inagaki Riichiro and illustrated by Murata Yuusuke. Its 333 chapters have spawned a 145-episode anime, two OVAs, music albums, videogames and miscellaneous merchandise.
The anime aired between 2005 and 2008.