When a character's eyes are pointed upwards relative to their face. This is often done to look cute, coy, childish, timid, submissive, or pleading.
This expression is sometimes accompanied by the head tilted downward, sometimes with face facing forward but looking up, often occurs alongside raised eyebrows. It also occurs when a character is looking at the viewer, but is below their eye-level (such as often the case with fellatio).
This is different from rolling eyes or eyes rolled back in the head (as in ahegao) in that in this case something is actively being focused on and looked at. This is similar to sanpaku in that the white sclera of their eyes might be visible to three of four sides of their irises, but in this tag refers to a soft, gentle expression, whereas sanpaku refers to a shocked, angry, detatched, or unhinged expression.